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| Registros recuperados : 16 | |
| 3. |  | MOREIRA, G. C. M.; PÉRTILLE, F.; GODOY, T. F.; BRASSOLOTI, R.; BOSCHIERO, C.; LEDUR, M. C.; COUTINHO, L. L. Discovery of candidate genes for fatness in chickens based on genotyping with 600K SNP chip in a QTL region. In: CONGRESSO BRASILEIRO DE GENÉTICA, 60., 2014, Guarujá. Resumos? Ribeirão Preto: Sociedade Brasileira de Genética, 2014. p. 64| Biblioteca(s): Embrapa Suínos e Aves. |
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| 4. | | PÉRTILLE, F.; ZANELLA, R.; FELÍCIO, A. M.; LEDUR, M. C.; PEIXOTO, J. de O.; COUTINHO, L. L. Identification of polymorphisms associated with production traits on chicken (Gallus gallus) chromosome 4. Genetics and Molecular Research, v. 14, n. 3, p. 10717-10728, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 5. | | PÉRTILLE, F.; TESSMANN, A. L.; COUTINHO, L. L.; AVILA, V. S. de; PEIXOTO, J. de O.; COLDEBELLA, A.; LEDUR, M. C. Investigation of the LEPR1 A>G polymorphism in the leptin receptor gene in a commercial broiler population. In: CONGRESSO BRASILEIRO DE GENÉTICA, 57., 2011, Águas de Lindóia. Resumos. Águas de Lindóia: SBG, 2011. p.103. Projeto/Plano de Ação: 01.06.10602-03.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 6. | | SILVA, V. H. da; REGITANO, L. C. de A.; GEISTLINGER, L.; PÉRTILLE, F.; GIACHETTO, P. F.; BRASSALOTI, R. A.; MOROSINI, N. S.; ZIMMER, R.; COUTINHO, L. L. Genome-wide detection of CNVs and their association with meat tenderness in Nelore cattle. Plos One, june 2016.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 7. | | PÉRTILLE, F.; BOSAGNA, C. G.; SILVA, V. H. da; BOSCHIERO, C.; NUNES, J. de R. da S.; LEDUR, M. C.; JENSEN, P.; COUTINHO, L. L. High-throughput and cost-effective chicken genotyping using next-generation sequencing. Scientific Reports, v. 6, n. 26929, 2016.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 8. | | PÉRTILLE, F.; FELÍCIO, A. M.; ROSÁRIO, M. F. do; SILVA, V. H.; MANGUETTI, T.; SILVA, N. A.; LEDUR, M. C.; COUTINHO, L. L. PPARGC1A indel polymorphism is associated with performance and carcass traits in chickens. In: CONGRESSO BRASILEIRO DE GENÉTICA, 58., 2012, Foz do Iguaçu. Resumos... Foz do Iguaçú: SBG, 2012. p. 72| Biblioteca(s): Embrapa Suínos e Aves. |
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| 9. | | PÉRTILLE, F.; IBELLI, A. M. G.; SHARIF, M. E.; POLETI, M. D.; FRÖHLICH, A. S.; REZAEI, S.; LEDUR, M. C.; JENSEN, P.; GUERRERO-BOSAGNA, C.; COUTINHO. L. L. Putative epigenetic biomarkers of stress in red blood cells of chickens reared across different biomes. Frontiers in Genetics, 20 Nov 2020.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 10. | | MOREIRA, G. C. M.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; GODOY, T. F.; PÉRTILLE, F.; LEDUR, M. C.; MOURA, A. S. A. M. T. M.; GARRICK, D. J.; COUTINHO, L. L. Integration of genome wide association studies and whole genome sequencing provides novel insights into fat deposition in chicken. Scientific Reports, v. 8, n. 16222, 2018.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 11. | | PERTILLE, F.; MOREIRA, G. C. M. M.; ZANELLA, R.; NUNES, J. de R. da S.; BOSCHIERO, C.; ROVADOSCKI, G. A.; MOURÃO, G. B.; LEDUR, M. C.; COUTINHO, L. L. Genome-wide association study for performance traits in chickens using genotype by sequencing approach. Scientific Reports, v. 7, n. 41748, 2017.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 12. | | ZANELLA, R.; LAGO, L. V.; SILVA, A. N. da; PÉRTILLE, F.; CARVALHO, N. S. de; PANETTO, J. C. do C.; ZANELLA, G. C.; FACIOLI, F. L.; SILVA, M. V. G. B. Genetic characterization of Indubrasil cattle breed population. Veterinary Sciences, v. 5, n. 4, 2018. 10 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 13. | | DAL PIZZOL, M. S.; IBELLI, A. M. G.; MORÉS, N.; MORES, M. A. Z.; PEIXOTO, J. de O.; SAVOLDI, I. R.; PERTILLE, F.; MARIANI, P. D. S. C.; COUTINHO, L. L.; LEDUR, M. C. Perfil de metilação diferencial no cromossomo 6 de suínos normais e afetados com osteocondrose latens. In: JORNADA DE INICIAÇÃO CIENTÍFICA, 13., 2019, Concórdia. Anais... Concórdia: Embrapa Suínos e Aves: UNC, 2019. p. 36-37. JINC 2019.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 14. | | DAL PIZZOL, M. S.; IBELLI, A. M. G.; SALMÓRIA, L. A.; MORES, M. A. Z.; PEIXOTO, J. de O.; SAVOLDI, I. R.; PERTILLE, F.; MARIANI, P. D. S. C.; COUTINHO, L. L.; LEDUR, M. C. Perfil de metilação diferencial em suínos normais e afetados com osteocondrose latens. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL ON-LINE, 14., 2021. Anais... Chapecó: UDESC: Concórdia: Embrapa Suínos e Aves, 2022.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 15. | | POLETI, M. D.; REGITANO, L. C. de A.; SOUZA, G. H. M. F.; CESAR, A. S. M.; SIMAS, R. C.; VIGNATTO, B. S.; MONTENEGRO, H.; PÉRTILLE, F.; BALIEIRO, J. C. C.; CAMERON, L. C.; ELER, J. P.; COUTINHO, L. L. Proteome alterations associated with the oleic acid and cis-9, trans-11 conjugated linoleic acid content in bovine skeletal muscle. Journal of Proteomics, v. 222, p. 1-14, e103792, jun. 2020.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 16. | | MOREIRA, G. C. M.; POLETI, M. D.; PÉRTILLE, F.; BOSCHIERO, C.; CESAR, A. S. M.; GODOY, T. F.; LEDUR, M. C.; REECY, J. M.; GARRICK, D. J.; COUTINHO, L. L. Unraveling genomic associations with feed efficiency and body weight traits in chickens through an integrative approach. BMC Genetics, v. 20, n. 83, 2019.| Biblioteca(s): Embrapa Suínos e Aves. |
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| Registros recuperados : 16 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
20/10/2016 |
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Data da última atualização: |
01/04/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SILVA, V. H. da; REGITANO, L. C. de A.; GEISTLINGER, L.; PÉRTILLE, F.; GIACHETTO, P. F.; BRASSALOTI, R. A.; MOROSINI, N. S.; ZIMMER, R.; COUTINHO, L. L. |
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Afiliação: |
VINICIUS HENRIQUE DA SILVA, USP/ESALQ; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; LUDWIG GEISTLINGER, Ludwig-Maximilians- Universität München; FÁBIO PÉRTILLE, USP/ESALQ; POLIANA FERNANDA GIACHETTO, CNPTIA; RICARDO AUGUSTO BRASSALOTI, USP/ESALQ; NATÁLIA SILVA MOROSINI, USP/ESALQ; RALF ZIMMER, Ludwig-Maximilians- Universität München; LUIZ LEHMANN COUTINHO, USP/ESALQ. |
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Título: |
Genome-wide detection of CNVs and their association with meat tenderness in Nelore cattle. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Plos One, june 2016. |
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DOI: |
10.1371/journal.pone.0157711 |
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Idioma: |
Inglês |
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Conteúdo: |
Brazil is one of the largest beef producers and exporters in the world with the Nelore breed representing the vast majority of Brazilian cattle (Bos taurus indicus). Despite the great adaptability of the Nelore breed to tropical climate, meat tenderness (MT) remains to be improved. Several factors including genetic composition can influence MT. In this article, we report a genome-wide analysis of copy number variation (CNV) inferred from Illumina1 High Density SNP-chip data for a Nelore population of 723 males. We detected >2,600 CNV regions (CNVRs) representing 6.5% of the genome. Comparing our results with previous studies revealed an overlap in 1400 CNVRs (>50%). A total of 1,155 CNVRs (43.6%) overlapped 2,750 genes. They were enriched for processes involving guanosine triphosphate (GTP), previously reported to influence skeletal muscle physiology and morphology. Nelore CNVRs also overlapped QTLs for MT reported in other breeds (8.9%, 236 CNVRs) and from a previous study with this population (4.1%, 109 CNVRs). Two CNVRs were also proximal to glutathione metabolism genes that were previously associated with MT. Genome-wide association study of CN state with estimated breeding values derived from meat shear force identified 6 regions, including a region on BTA3 that contains genes of the cAMP and cGMP pathway. Ten CNVRs that overlapped regions associated with MT were successfully validated by qPCR. Our results represent the first comprehensive CNV study in Bos taurus indicus cattle and identify regions in which copy number changes are potentially of importance for the MT phenotype. MenosBrazil is one of the largest beef producers and exporters in the world with the Nelore breed representing the vast majority of Brazilian cattle (Bos taurus indicus). Despite the great adaptability of the Nelore breed to tropical climate, meat tenderness (MT) remains to be improved. Several factors including genetic composition can influence MT. In this article, we report a genome-wide analysis of copy number variation (CNV) inferred from Illumina1 High Density SNP-chip data for a Nelore population of 723 males. We detected >2,600 CNV regions (CNVRs) representing 6.5% of the genome. Comparing our results with previous studies revealed an overlap in 1400 CNVRs (>50%). A total of 1,155 CNVRs (43.6%) overlapped 2,750 genes. They were enriched for processes involving guanosine triphosphate (GTP), previously reported to influence skeletal muscle physiology and morphology. Nelore CNVRs also overlapped QTLs for MT reported in other breeds (8.9%, 236 CNVRs) and from a previous study with this population (4.1%, 109 CNVRs). Two CNVRs were also proximal to glutathione metabolism genes that were previously associated with MT. Genome-wide association study of CN state with estimated breeding values derived from meat shear force identified 6 regions, including a region on BTA3 that contains genes of the cAMP and cGMP pathway. Ten CNVRs that overlapped regions associated with MT were successfully validated by qPCR. Our results represent the first comprehensive CNV study in Bos taurus indicu... Mostrar Tudo |
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Palavras-Chave: |
CNV; Genômica; Maciez da carne; Nelore. |
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Thesagro: |
Gado Nelore. |
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Thesaurus NAL: |
Meat tenderness. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/149047/1/pone.0157711.pdf
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Marc: |
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024 7 $a10.1371/journal.pone.0157711$2DOI
100 1 $aSILVA, V. H. da
245 $aGenome-wide detection of CNVs and their association with meat tenderness in Nelore cattle.$h[electronic resource]
260 $c2016
520 $aBrazil is one of the largest beef producers and exporters in the world with the Nelore breed representing the vast majority of Brazilian cattle (Bos taurus indicus). Despite the great adaptability of the Nelore breed to tropical climate, meat tenderness (MT) remains to be improved. Several factors including genetic composition can influence MT. In this article, we report a genome-wide analysis of copy number variation (CNV) inferred from Illumina1 High Density SNP-chip data for a Nelore population of 723 males. We detected >2,600 CNV regions (CNVRs) representing 6.5% of the genome. Comparing our results with previous studies revealed an overlap in 1400 CNVRs (>50%). A total of 1,155 CNVRs (43.6%) overlapped 2,750 genes. They were enriched for processes involving guanosine triphosphate (GTP), previously reported to influence skeletal muscle physiology and morphology. Nelore CNVRs also overlapped QTLs for MT reported in other breeds (8.9%, 236 CNVRs) and from a previous study with this population (4.1%, 109 CNVRs). Two CNVRs were also proximal to glutathione metabolism genes that were previously associated with MT. Genome-wide association study of CN state with estimated breeding values derived from meat shear force identified 6 regions, including a region on BTA3 that contains genes of the cAMP and cGMP pathway. Ten CNVRs that overlapped regions associated with MT were successfully validated by qPCR. Our results represent the first comprehensive CNV study in Bos taurus indicus cattle and identify regions in which copy number changes are potentially of importance for the MT phenotype.
650 $aMeat tenderness
650 $aGado Nelore
653 $aCNV
653 $aGenômica
653 $aMaciez da carne
653 $aNelore
700 1 $aREGITANO, L. C. de A.
700 1 $aGEISTLINGER, L.
700 1 $aPÉRTILLE, F.
700 1 $aGIACHETTO, P. F.
700 1 $aBRASSALOTI, R. A.
700 1 $aMOROSINI, N. S.
700 1 $aZIMMER, R.
700 1 $aCOUTINHO, L. L.
773 $tPlos One, june 2016.
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Embrapa Pecuária Sudeste (CPPSE) |
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